A report on the ability of common aluminum containing vaccine adjuvants to cause inflammation in isolated cell lines.
Highlights
- Aluminum based adjuvants (ABAs) decrease viability in astrocytes and macrophages.
- Size of aluminum particles influence viability to some extent.
- Reactive oxygen species formation is consequent to loss of cell viability.
- After ABA exposure, cytokine production is distinct based on cell type evaluated.
Authors
Isaac Nies, Krisha Hidalgo, Stephen C. Bondy, Arezoo Campbell
